About EAM2201 US

About EAM2201 US

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The intention of the analyze is always to characterize the metabolites of EAM-2201 in human hepatocytes received in vitro and people in liver and urine specimens received in vivo from the autopsy of the EAM-2201 abuser.

Twelve metabolites of a artificial cannabinoid, EAM-2201, ended up tentatively determined in human hepatocytes in vitro, and in human liver and urine specimens in vivo for The 1st time. There was a definite big more info difference in metabolism profile among the in vitro As well as in vivo effects.

EAM-2201 was incubated with human hepatocytes for three h within a CO2 incubator and the metabolites of EAM-2201 were generated. The human liver specimen was homogenized as well as the metabolites were extracted. The urine specimen was hydrolyzed 1st with β-glucuronidase and also the metabolites ended up extracted.

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